*Submissions that get read and noticed are the "high concept" ones in which the author describes clearly in just a few sentences what his/her book is about. Ex. Jane Austen meets James Bond.
*A short one-page synopsis is best.
*Personalize your queries to agents you've researched and targeted. Same applies to work going to journals, poetry zines, magazines, etc.
*Social networking really is important for author platform/branding. Be accessible online.
*Remove snippets of your manuscripts from the Web so you're not stepping on agents/publishers efforts to sell your book, and to keep your work safe.
More "gooder" stuff next week!